| Company | Service | # of Employees |
| Cargill Meat Solutions | Retail meat processing facility | 700 |
| Bemis Company, Inc. | Extrusion & printing of polyfilm | 509 |
| Fabri-Kal Corporation | Packaging products | 483 |
| The Hershey Company | Molded chocolate products | 355 |
| Bimbo Bakeries, USA | Bakery food products | 348 |
| Worldcolor Hazleton | Printing of telephone directories | 320 |
| First Quality Nonwovens | Nonwoven fabric | 290 |
| Archer Daniels Midland | Cocoa products | 200 |
| Simmons Company | Mattresses | 195 |
| Silgan White Cap | Metal closures | 190 |
| The Dial Corporation | Household laundry products | 180 |
| Altadis USA, Inc. | Cigar boxes & wrappers | 177 |
| Valmont Newmark | Tubular steel poles | 129 |
| Pretium Packaging | PVC containers | 120 |
| Temple - Inland | Corrugated shipping containers | 111 |
| Gonnella Frozen Products, LLC. | Manufacturer of dough for in-store bakeries | 101 |
| Progressive Converting | Manufacturing/converting of high-quality paper | 100 |
